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INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2230821-40-4
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- SJF 1521;(2S,4R)-1-[(2S)-2-(2-{2-[2-(2-{4-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]phenoxy}ethoxy)ethoxy]ethoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CBNumber:
- CB78197600
- Molecular Formula:
- C57 H61 Cl F N7 O9 S
- Molecular Weight:
- 1074.66
- MDL Number:
- MOL File:
- 2230821-40-4.mol
Last updated:2024-10-28 23:16:16
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Description
SJF 1521 is a selective EGFR PROTAC?? Degrader based on the EGFR inhibitor lapatinib linked to a von Hippel-Lindau (VHL) recruiting ligand by PEG3. SJF 1521 exhibits selectivity for EGFR, including mutant forms, over HER2 and induces degradation of EGFR in OVCAR8 cells.
storage
Store at -20°C
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
Global( 12)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1466 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 17717813675; | malulu@leyan.com | China | 39988 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5018 | 58 |
SJF 1521
(2S,4R)-1-[(2S)-2-(2-{2-[2-(2-{4-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]phenoxy}ethoxy)ethoxy]ethoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
2230821-40-4
C57H61ClFN7O9S