ADRA1D receptor agonist 1
- CAS No.
- 1191908-14-1
- Chemical Name:
- ADRA1D receptor agonist 1
- Synonyms
- ADRA1D receptor agonist 1;ADRA1D receptor antagonist 1;ADRA1D receptor antagonist 1 HCl;ADRA-1D receptor antagonist 1,ADRA1D receptor antagonist 1
- CBNumber:
- CB78054299
- Molecular Formula:
- C15H14Cl2N4O
- Molecular Weight:
- 337.2
- MDL Number:
- MFCD34469748
- MOL File:
- 1191908-14-1.mol
ADRA1D receptor agonist 1 Chemical Properties,Uses,Production
Uses
ADRA1D receptor antagonist 1 is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM[1].
in vivo
ADRA1D receptor antagonist 1 (4.4 μg/kg; i.v.) dose-dependently decreases the non-voiding bladder contractions during the urinary storage phase in rats with BOO[1].
| Animal Model: | Rat with bladder outlet obstruction (BOO)[1] |
| Dosage: | 4.4 μg/kg |
| Administration: | Intravenous injection |
| Result: | Dose-dependently decreased the non-voiding bladder contractions during urinary storage phase in rats with BOO. |
References
[1] Sakauchi N, et al. Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide (TAK-259) as a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist with Antiurinary Frequency Effects: Reducing Human Ethe DOI:10.1021/acs.jmedchem.5b01528
ADRA1D receptor agonist 1 Preparation Products And Raw materials
Raw materials
Preparation Products
ADRA1D receptor agonist 1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32295 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38671 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19904 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29770 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 21630 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 6710 | 58 |
View Lastest Price from ADRA1D receptor agonist 1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-30 | ADRA1D receptor antagonist 1 HCl
1191908-14-1
|
US $199.00 / mg | 98.13% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-29 | ADRA1D receptor antagonist 1 HCl
1191908-14-1
|
US $199.00 / mg | 98.13% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-28 | ADRA1D receptor antagonist 1 HCl
1191908-14-1
|
US $199.00 / mg | 98.13% | 10g | TargetMol Chemicals Inc. |
-
- ADRA1D receptor antagonist 1 HCl
1191908-14-1
- US $199.00 / mg
- 98.13%
- TargetMol Chemicals Inc.
-
- ADRA1D receptor antagonist 1 HCl
1191908-14-1
- US $199.00 / mg
- 98.13%
- TargetMol Chemicals Inc.
-
- ADRA1D receptor antagonist 1 HCl
1191908-14-1
- US $199.00 / mg
- 98.13%
- TargetMol Chemicals Inc.