1H-Indazol-5-ol, 4-chloro-
- CAS No.
- 478834-25-2
- Chemical Name:
- 1H-Indazol-5-ol, 4-chloro-
- Synonyms
- 4-Chloro-1H-indazol-5-ol;1H-Indazol-5-ol, 4-chloro-;4-Chloro-4-hydroxy-1H-indazole
- CBNumber:
- CB71868419
- Molecular Formula:
- C7H5ClN2O
- Molecular Weight:
- 168.58
- MDL Number:
- MFCD16659073
- MOL File:
- 478834-25-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
1H-Indazol-5-ol, 4-chloro- price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C384633 | 4-Chloro-1H-indazol-5-ol | 478834-25-2 | 10mg | $110 | 2021-12-16 | Buy |
| AK Scientific | 6007DA | 4-Chloro-1H-indazol-5-ol | 478834-25-2 | 250mg | $232 | 2021-12-16 | Buy |
| Chemenu | CM123050 | 4-chloro-1H-indazol-5-ol 98% | 478834-25-2 | 1g | $234 | 2021-12-16 | Buy |
| Crysdot | CD11118183 | 4-Chloro-1H-indazol-5-ol 98% | 478834-25-2 | 1g | $248 | 2021-12-16 | Buy |
| Alichem | 478834252 | 4-Chloro-1H-indazol-5-ol | 478834-25-2 | 1g | $275 | 2021-12-16 | Buy |
1H-Indazol-5-ol, 4-chloro- Chemical Properties,Uses,Production
Chemical Properties
Solid
Synthesis
15579-15-4
478834-25-2
At room temperature, 1H-indazol-5-ol (1.60 g, 11.9 mmol) was dissolved in tetrahydrofuran (50 mL) and N-chlorosuccinimide (1.59 g, 11.9 mmol) was added. After 1 hour of reaction, the mixture was warmed up to 40 °C to continue the reaction for 2 hours, followed by warming up to 50 °C for 5 hours. Upon completion of the reaction, the reaction solution was poured into water (100 mL) and extracted with ethyl acetate (3 × 100 mL). The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford 4-chloro-5-hydroxy-1H-indazole (1.7365 g, 86% yield).1H-NMR (DMSO-d6) δ: 7.09 (1H, d, J = 8.8 Hz), 7.33 (1H, d, J = 8.8 Hz), 7.90 (1H, s) 9.71 (1H, s), 13.10 (1H, s).
References
[1] Patent: EP1403255, 2004, A1. Location in patent: Page 120
1H-Indazol-5-ol, 4-chloro- Preparation Products And Raw materials
1H-Indazol-5-ol, 4-chloro- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42953 | 64 |
| Shanghai Huikai Chemical Technology Co., Ltd. | 021-61995394 18916691159 | chemicalsea@163.com | China | 1972 | 58 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10263 | 55 |
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| Chengdu DingDang Pharmaceutical Co., Ltd. | 028-86040038 13980902949; | market@dingdangchem.com | China | 1853 | 55 |
