ChemicalBook >> CAS DataBase List >>SC-VC-PAB-MMAE
SC-VC-PAB-MMAE
- CAS No.
- 2259318-46-0
- Chemical Name:
- SC-VC-PAB-MMAE
- Synonyms
- SC-VC-PAB-MMAE;2,5-Dioxopyrrolidin-1-yl 6-(((S)-1-(((S)-1-((4-((5S,8S,11S,12R)-11-((S)-sec-butyl)-12-(2-((S)-2-((1R;2,5-Dioxopyrrolidin-1-yl 6-(((S)-1-(((S)-1-((4-((5S,8S,11S,12R)-11-((S)-sec-butyl)-12-(2-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradecyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-6-oxohexanoate
- CBNumber:
- CB65821163
- Molecular Formula:
- C68H105N11O17
- Molecular Weight:
- 1348.63
- MDL Number:
- MFCD32689556
- MOL File:
- 2259318-46-0.mol
Last updated:2025-04-17 18:22:24
SC-VC-PAB-MMAE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0106796 | SC-VC-PAB-MMAE 96.23% | 2259318-46-0 | 1mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0106796 | SC-VC-PAB-MMAE 96.23% | 2259318-46-0 | 5mg | $1050 | 2021-12-16 | Buy |
| ChemScene | CS-0106796 | SC-VC-PAB-MMAE 96.23% | 2259318-46-0 | 10mg | $1950 | 2021-12-16 | Buy |
SC-VC-PAB-MMAE Chemical Properties,Uses,Production
Uses
SC-VC-PAB-MMAE is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB[1].
IC 50
Auristatin
References
[1] Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.
SC-VC-PAB-MMAE Preparation Products And Raw materials
Raw materials
Preparation Products
SC-VC-PAB-MMAE Suppliers
Global( 12)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32285 | 58 |
| ChemExpress | +86-021-58950125 +86-021-58950125; | info@chemexpress.com | China | 785 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3663 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Wuxi Kehua Biological Technology Co., Ltd. | 0510-0510-86838766 | 2258830676@qq.com | China | 4608 | 58 |
| Shanghai Haoyuan Chemexpress Co., Ltd. | 021-51870955 | info@chemexpress.com | China | 810 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13173652190 | pomy@tanzhenbio.com | China | 1903 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59102966 18717199209 | 2853877583@qq.com | China | 2993 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62321 | 58 |
| nanjing | 13376082704 13376082704 | 3930959291@qq.com | China | 2905 | 58 |
SC-VC-PAB-MMAE
2,5-Dioxopyrrolidin-1-yl 6-(((S)-1-(((S)-1-((4-((5S,8S,11S,12R)-11-((S)-sec-butyl)-12-(2-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradecyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-6-oxohexanoate
2,5-Dioxopyrrolidin-1-yl 6-(((S)-1-(((S)-1-((4-((5S,8S,11S,12R)-11-((S)-sec-butyl)-12-(2-((S)-2-((1R
2259318-46-0
C68H105N11O17
ADC LINKER