RTIL 13
- CAS No.
- 1009376-10-6
- Chemical Name:
- RTIL 13
- Synonyms
- RTIL 13;RTIL 13, dynamin I and II inhibitor;4-(N,N-Dimethyl-N-octadecyl-N-ethyl)-4-aza-10-oxatricyclo-[5.2.1]decane-3,5-dionebromide
- CBNumber:
- CB63152984
- Molecular Formula:
- C30H55BrN2O3
- Molecular Weight:
- 571.69
- MDL Number:
- MOL File:
- 1009376-10-6.mol
RTIL 13 Chemical Properties,Uses,Production
Uses
RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 μM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[1][2].
References
[1] Zhang J, et, al. From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs. New Journal of Chemistry. 2008 Jan; 32(1): 1-180.
[2] Ascent Scientific Launch Novel Dynamin Inhibitor Dyngo-4a? with Children's Medical Research Institute and University of Newcastle. Tuesday, December 28, 2021.
RTIL 13 Preparation Products And Raw materials
Raw materials
Preparation Products
RTIL 13 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 24072 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 23263 | 58 |
| Supplier | Advantage |
|---|---|
| Alfa Chemistry | 58 |
| Aladdin Scientific | 58 |
| TargetMol Chemicals Inc. | 58 |