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ChemicalBook >> CAS DataBase List >>Akebia saponin D

Akebia saponin D

CAS No.
39524-08-8
Chemical Name:
Akebia saponin D
Synonyms
Asperosap;AkebosideD;Asperosaponin Ⅵ;Asperosaponin VI;Akebia saponin D;Dipsacaceae saponin;Asperosaponin VI-RM;Akebia saponin D USP/EP/BP;Asperosaponin VI (Akeboside D);Asperosaponin VI, 10 mM in DMSO
CBNumber:
CB61267734
Molecular Formula:
C47H76O18
Molecular Weight:
929.1
MDL Number:
MFCD25371916
MOL File:
39524-08-8.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

Akebia saponin D Properties

Melting point 234-235 °C
Boiling point 990.2±65.0 °C(Predicted)
Density 1.43
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form Solid
pka 12.50±0.70(Predicted)
color White to Pale Beige
optical activity [α]/D +13 to +18°, c =0.5 in methanol
biological source (Dipsacus asper)
Water Solubility H2O: 3mg/mL, clear (warmed)
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Safety Statements  24/25
HS Code  29389090

Akebia saponin D price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL83275 Asperosaponin VI phyproof? Reference Substance 39524-08-8 10MG $550 2024-03-01 Buy
TRC A788600 AsperosaponinVI 39524-08-8 10mg $150 2021-12-16 Buy
Usbiological 299958 Asperosaponin VI 39524-08-8 20mg $390 2021-12-16 Buy
ChemScene CS-0008286 AsperosaponinVI 98.73% 39524-08-8 20mg $150 2021-12-16 Buy
Biorbyt Ltd orb104638 Akebia saponin D >98%,Standard References Grade 39524-08-8 20mg $569.5 2021-12-16 Buy
Product number Packaging Price Buy
PHL83275 10MG $550 Buy
A788600 10mg $150 Buy
299958 20mg $390 Buy
CS-0008286 20mg $150 Buy
orb104638 20mg $569.5 Buy

Akebia saponin D Chemical Properties,Uses,Production

Uses

Asperosaponin VI is a steroidal extract with anti-inflammatory and antinociceptive activity. long term use has been seen to attenuate cardiac dysfunction.

Definition

ChEBI: Akebia saponin D is a triterpenoid saponin that is hederagenin attached to a alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage and a 6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 28 via an ester linkage. It is the active ingredient found in the traditional Chinese herb Radix Dipsaci. It has a role as an apoptosis inducer, an antineoplastic agent, a plant metabolite, an anti-inflammatory agent, a bone density conservation agent, a neuroprotective agent and an antilipemic drug. It is a triterpenoid saponin, a trisaccharide derivative, a pentacyclic triterpenoid and a carboxylic ester. It is functionally related to a hederagenin.

Biological Activity

Akebia saponin D (ASD) is a bioactive triterpenoid saponin isolated from the rhizome of Dipsacus asper Wall th at is used as an anti-osteoporosis drug. Akebia saponin D exhibits therapeutic effects in number of disease models including cancer, Alzheimerμs disease, cardiovascular disease, and bone fractures. Akebia saponin D protects against nonalcoholic fatty liver disease (NAFLD) liver damage in mice model of NAFLD. ASD decreases hepatic steatosis and heptocyte apoptosis through autophagy modulation. Akebia saponin D prevents oleic acid induced lipid droplets accumulation and increases autophagic flux BRL cells.

Akebia saponin D Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 198)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21631 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29863 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58

View Lastest Price from Akebia saponin D manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Asperosaponin VI pictures 2024-11-19 Asperosaponin VI
39524-08-8
 US $60.00 / mg 99.79% 10g TargetMol Chemicals Inc.
Akebia saponin D pictures 2023-02-24 Akebia saponin D
39524-08-8
 US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Akebia saponin D pictures 2023-02-24 Akebia saponin D
39524-08-8
 US $0.00 / mg 5mg Analytical Standard 10 g Shanghai Standard Technology Co., Ltd.
  • Akebia saponin D pictures
  • Akebia saponin D
    39524-08-8
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Akebia saponin D pictures
  • Akebia saponin D
    39524-08-8
  • US $0.00 / mg
  • Analytical Standard
  • Shanghai Standard Technology Co., Ltd.

Akebia saponin D Spectrum

Akebia saponin D Asperosaponin VI Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1→6)-beta-D-glucopyranoside Akebia saponin D(Asperosaponin VI) Dipsacaceae saponin Asperosaponin Ⅵ 3'-Amino-2'-Hydroxy-1,1' biphenyl-3-cAsperosaponin VI Asperosaponin VI, 98%, from Dipsacales Asperosaponin VI (Akeboside D) AkebosideD Olean-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-23-hydroxy-, 6-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (3β,4α)- Akebia saponin D USP/EP/BP TIANFUCHEM--39524-08-8--High purity Akebia saponin D factory price Asperosap 1-O-[(3b)-3-(a-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-b-D-glucopyranose (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate Asperosaponin VI-RM 3’-Amino-2’-Hydroxy-1,1’ biphenyl-3-cAsperosaponin VI Asperosaponin VI, 10 mM in DMSO 39524-08-8 C47H76O18 Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract