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ChemicalBook >> CAS DataBase List >>2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)-

2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)-

CAS No.
794544-99-3
Chemical Name:
2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)-
Synonyms
TAS4;TAS-4;TAS 4;2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)-
CBNumber:
CB510695592
Molecular Formula:
C12H8Cl2N2O
Molecular Weight:
267.11
MDL Number:
MOL File:
794544-99-3.mol
Last updated:2025-04-18 09:52:22

2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- Properties

Boiling point 318.1±37.0 °C(Predicted)
Density 1.440±0.06 g/cm3(Predicted)
pka 10.10±0.70(Predicted)

2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- Chemical Properties,Uses,Production

Description

TAS-4 is a metabotropic glutamate receptor 4-positive allosteric modulator.

Uses

TAS-4 is a potent and selective mGluR4 positive allosteric modulator with significant anti-Parkinson's disease activity. TAS-4 is able to show efficacy when used alone or in combination with l-DOPA. TAS-4 is able to reverse haloperidol-induced spasticity when administered alone. TAS-4 enhances the contralateral rotation behavior induced by l-DOPA in a dose-dependent manner. TAS-4 combined with low-dose l-DOPA shows anti-Parkinson's effects similar to full-dose l-DOPA without exacerbating abnormal motor side effects[1].

References

[1] Therapeutic potential of metabotropic glutamate receptor 4-positive allosteric modulator TAS-4 in rodent models of movement disorders DOI:10.1016/j.jns.2014.07.008

2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32295 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19904 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4744 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21630 58
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 780229652@qq.com China 1262 58

View Lastest Price from 2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TAS-4 pictures 2024-10-28 TAS-4
794544-99-3
 US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • TAS-4 pictures
  • TAS-4
    794544-99-3
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
2-Pyridinecarboxamide, N-(2,4-dichlorophenyl)- TAS 4 TAS4 TAS-4 794544-99-3