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ChemicalBook >> CAS DataBase List >>4-(1-Acetylpiperazin-4-yl)phenol

4-(1-Acetylpiperazin-4-yl)phenol

CAS No.
67914-60-7
Chemical Name:
4-(1-Acetylpiperazin-4-yl)phenol
Synonyms
1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE;AHPP;keto06;TIMTEC-BB SBB003353;Ketoconazole Impurity;LABOTEST-BB LT00440741;Ketoconazole Impurity 13;Branchedchainofketoconazole;4-(4-Acetylpiperazino)phenol;1-Acetyl-4-(4-hydroxyphenyl)pi
CBNumber:
CB4329307
Molecular Formula:
C12H16N2O2
Molecular Weight:
220.27
MDL Number:
MFCD00044905
MOL File:
67914-60-7.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

4-(1-Acetylpiperazin-4-yl)phenol Properties

Melting point 180-185 °C (lit.)
Boiling point 361.21°C (rough estimate)
Density 1.1115 (rough estimate)
vapor pressure 0Pa at 20℃
refractive index 1.6000 (estimate)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Powder
pka 12.18±0.30(Predicted)
color White to slightly pink or beige
Water Solubility 4.3 g/L (20 ºC)
BRN 795777
InChIKey AGVNLFCRZULMKK-UHFFFAOYSA-N
LogP 0.3
CAS DataBase Reference 67914-60-7(CAS DataBase Reference)
FDA UNII YH9GD5K5NY
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-36/37/39-22
WGK Germany  3
HS Code  29214910
NFPA 704
1
2 0

4-(1-Acetylpiperazin-4-yl)phenol price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 511943 1-Acetyl-4-(4-hydroxyphenyl)piperazine 98% 67914-60-7 25g $31.5 2023-06-20 Buy
TCI Chemical A1845 1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T) 67914-60-7 25g $22 2024-03-01 Buy
TCI Chemical A1845 1-Acetyl-4-(4-hydroxyphenyl)piperazine >98.0%(GC)(T) 67914-60-7 250g $122 2024-03-01 Buy
Alfa Aesar B22083 1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98% 67914-60-7 100g $81 2021-12-16 Buy
Alfa Aesar B22083 1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98% 67914-60-7 25g $26.9 2021-12-16 Buy
Product number Packaging Price Buy
511943 25g $31.5 Buy
A1845 25g $22 Buy
A1845 250g $122 Buy
B22083 100g $81 Buy
B22083 25g $26.9 Buy

4-(1-Acetylpiperazin-4-yl)phenol Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.

General Description

1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen. Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2

Flammability and Explosibility

Not classified

4-(1-Acetylpiperazin-4-yl)phenol Preparation Products And Raw materials

Global( 401)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Jinhuan Chemical CO.,LTD.
+86-21-52210535 +8613162045318 sales@jinhchem.com China 331 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21629 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29861 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58

View Lastest Price from 4-(1-Acetylpiperazin-4-yl)phenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(1-Acetylpiperazin-4-yl)phenol pictures 2025-04-04 4-(1-Acetylpiperazin-4-yl)phenol
67914-60-7
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1- acetyl -4-(4-hydroxyphenyl) piperazine pictures 2021-12-22 1- acetyl -4-(4-hydroxyphenyl) piperazine
67914-60-7
 US $1.00 / g 1KG 99% 5ton/Month Qiuxian Baitai New Material Co., LTD
4-(1-Acetylpiperazin-4-yl)phenol pictures 2020-04-25 4-(1-Acetylpiperazin-4-yl)phenol
67914-60-7
 US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd

4-(1-Acetylpiperazin-4-yl)phenol Spectrum

TIMTEC-BB SBB003353 N-ACETYL-4-HYDROXYPHENYL PIPERAZINE N-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE 1-Acetyl-4-(4-hydroxyphenyl)piperazine, 98+% 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanon Piperazine, 1-acetyl-4-(4-hydroxyphenyl)- 1-Acetyl-4-(4-Hydroxy-Phenyl)PiperazineKetoconazole 4-(4-Acetylpiperazino)phenol 4-(4-acetylpiperazin-1-yl)phenol 1-Acety-(4-hyroxypheny)piperazine 1-(4-hydroxyphenyl)-4-acetylpiperazine 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone Ketoconazole IMpurity (1-Acetyl-4-(4-hydroxyphenyl)piperazine) Ethanone, 1- [4- (4- hydroxyphenyl) - 1- piperazinyl] - keto06 1-ACETYL-4-(4-HYDROXY PHENYL)PIPERAZINE (BRANCHED CHAIN) (PIPERAZINE RING IN STRUCTURE) Branchedchainofketoconazole 1-ACETYL-P-HYDROXYPHENYL PIPERAZINE 1-ACETYL-(4-HYDROXYPHENYL)PIPERAZINE 1-ACETYL-4-(4-HYDROXYLPHENYL)PIPERAZINE 1-ACETYL-4-(4'-HYDROXYPHENYL)PIPERAZINE 1-[4-(4-HYDROXY-PHENYL)-PIPERAZIN-1-YL]-ETHANONE 1-[4-(4-HYDROXYPHENYL)PIPERAZINO]ETHAN-1-ONE 4-(1-Acetylpiperazin-4-yl)phenol 4-(4-ACETYL-1-PIPERAZINYL)PHENOL LABOTEST-BB LT00440741 4-(4-Acetyl-1-piperazino)phenol 4-(4-acetylpiperazin-4-yl)phenol 1-Acetyl-4-(4-hydroxyphenyl)pi 1-ACETYL-4-(4-HYDROXPHENYL)PIPERAZINE 1-Acetyl-4-(p-hydroxyphenyl)piperazine 4-AHPP : 1-Acetyl-4-(4-Hydroxy Phenyl) Piperazine 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE (4AHPP) 1-Acetyl-4-(4-hydroxyphenyl)piperazine > 1-Acetyl-4-(4-hydroxyphenyl)piperaz Ketoconazole Impurity 13 1-Acetyl-4-(4-hydroxyphenyl) piperazie 4-(4-tert-butylphenyl)-2-(1-methyl-3-indolyl)-4-oxobutanoic acid Ketoconazole Impurity 1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP) Ketoconazole Impurity 13 (1-Acetyl-4-(4-hydroxyphenyl)piperazine) 1-Acetyl-4-(HydroxyPhenyl)Piprazine 1-ACETYL-4-(4-HYDROXYPHENYL)PIPERAZINE AHPP 1-Acetyl-4-(4-Hydroxyphenyl)Piperzine 1-Acetyt-4-(4-Hydroxyphenyl) Piperazine N-AcetyI-(4-Hydroxy Phenyl) Piperazine n-Acetyl 4-(4-Hydroxy phenyl) Piperizine 67914-60-7 67914-60-4 C12H16O2N2 Piperazines Heterocyclic Building Blocks Building Blocks Piperaizine Miscellaneous Chemical Amines Amines