Benzo[b]thiophene-2-carboxamide,N-phenyl-
- CAS No.
- 6314-40-5
- Chemical Name:
- Benzo[b]thiophene-2-carboxamide,N-phenyl-
- Synonyms
- Aβ42 agonist-2;N-PHENYL-1-BENZOTHIOPHENE-2-CARBOXAMIDE;N-Phenylbenzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide,N-phenyl-
- CBNumber:
- CB43232837
- Molecular Formula:
- C15H11NOS
- Molecular Weight:
- 253.31894
- MDL Number:
- MOL File:
- 6314-40-5.mol
Benzo[b]thiophene-2-carboxamide,N-phenyl- Chemical Properties,Uses,Production
Uses
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].
Synthesis Reference(s)
Tetrahedron, 34, p. 3545, 1978 DOI: 10.1016/0040-4020(78)88430-0
References
[1] Zhao Y et al. Small Molecules N-Phenylbenzofuran-2-carboxamide and N-Phenylbenzo[b]thiophene-2-carboxamide Promote Beta-Amyloid (Aβ42) Aggregation and Mitigate Neurotoxicity. ACS Chem Neurosci. 2023 Nov 16. DOI:10.1021/acschemneuro.3c00576
Benzo[b]thiophene-2-carboxamide,N-phenyl- Preparation Products And Raw materials
Benzo[b]thiophene-2-carboxamide,N-phenyl- Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6439 | 55 |
Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 | Sales@ATKchemical.com | China | 9342 | 58 |
Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4764 | 58 |
Shaoguan Qicheng Biotechnology Co., Ltd | 18122215013 | 780229652@qq.com | China | 1267 | 58 |
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-58851090 17714375163 | 2881759498@qq.com | China | 13012 | 58 |
Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 292394 | 58 |