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ChemicalBook >> CAS DataBase List >>MK-4827 (R-enantioMer)

MK-4827 (R-enantioMer)

CAS No.
1038915-58-0
Chemical Name:
MK-4827 (R-enantioMer)
Synonyms
(R)-Niraparib;ent-Niraparib;ent-Nirapanib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;Niraparib R-enantiomer p-tosylate
CBNumber:
CB42716288
Molecular Formula:
C19H20N4O
Molecular Weight:
320.39
MDL Number:
MOL File:
1038915-58-0.mol
Last updated:2024-11-19 20:33:22

MK-4827 (R-enantioMer) Properties

Boiling point 463.6±45.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 32 mg/mL (99.88 mM)
pka 15.36±0.30(Predicted)
form Solid
color Light yellow to yellow

MK-4827 (R-enantioMer) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC N481410 ent-Niraparib 1038915-58-0 500mg $2230 2021-12-16 Buy
ChemScene CS-3085 NiraparibR-enantiomer 99.50% 1038915-58-0 5mg $220 2021-12-16 Buy
ChemScene CS-3085 NiraparibR-enantiomer 99.50% 1038915-58-0 10mg $380 2021-12-16 Buy
ChemScene CS-3085 NiraparibR-enantiomer 99.50% 1038915-58-0 50mg $990 2021-12-16 Buy
Crysdot CD00013477 (R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 97% 1038915-58-0 1g $3294 2021-12-16 Buy
Product number Packaging Price Buy
N481410 500mg $2230 Buy
CS-3085 5mg $220 Buy
CS-3085 10mg $380 Buy
CS-3085 50mg $990 Buy
CD00013477 1g $3294 Buy

MK-4827 (R-enantioMer) Chemical Properties,Uses,Production

Uses

ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Definition

ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.

MK-4827 (R-enantioMer) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30231 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422 sale@hdimpurity.com China 3564 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 6335 58

View Lastest Price from MK-4827 (R-enantioMer) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-Niraparib pictures 2025-03-04 (R)-Niraparib
1038915-58-0
 US $0.00-0.00 / mg 10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
Niraparib (R-enantiomer) pictures 2024-11-19 Niraparib (R-enantiomer)
1038915-58-0
 US $44.00-187.00 / mg 99.41% 10g TargetMol Chemicals Inc.
Niraparib (R-enantiomer) pictures 2024-11-19 Niraparib (R-enantiomer)
1038915-58-0
 US $44.00-187.00 / mg 99.41% 10g TargetMol Chemicals Inc.
  • (R)-Niraparib pictures
  • (R)-Niraparib
    1038915-58-0
  • US $0.00-0.00 / mg
  • 0.98
  • ShenZhen H&D Pharmaceutical Technology Co., LTD
MK-4827 (R-enantioMer) Niraparib Impurity R isomer of MK-4827, Niraparib (R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE Niraparib R-enantiomer 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide ent-Niraparib 2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]- poly ADP ribose polymerase,Inhibitor,Niraparib (R enantiomer),PARP,Niraparib (Renantiomer),Niraparib (R-enantiomer),inhibit (R)-Niraparib Niraparib Impurity 13 ent-Nirapanib Niraparib Impurity 51 Niraparib R-enantiomer p-tosylate Niraparib (R-enantiomer), 10 mM in DMSO 1038915-58-0