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ChemicalBook >> CAS DataBase List >>S-1-Propenyl-L-cysteine

S-1-Propenyl-L-cysteine

CAS No.
52438-09-2
Chemical Name:
S-1-Propenyl-L-cysteine
Synonyms
S-1-Propenyl-L-cysteine;L-Cysteine, S-1-propen-1-yl-;S 1 Propenyl L cysteine,S1PropenylLcysteine
CBNumber:
CB38054529
Molecular Formula:
C6H11NO2S
Molecular Weight:
161.22
MDL Number:
MFCD29919772
MOL File:
52438-09-2.mol
Last updated:2025-04-18 09:52:09

S-1-Propenyl-L-cysteine Properties

Boiling point 301.1±37.0 °C(Predicted)
Density 1.204±0.06 g/cm3(Predicted)
pka 2.07±0.10(Predicted)
form Solid
color White to off-white

S-1-Propenyl-L-cysteine Chemical Properties,Uses,Production

Uses

S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model[1]. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway[2]. S-1-Propenyl-L-cysteine is orally active.

in vivo

S-1-Propenyl-L-cysteine (6.5 mg/kg, p.o.) reduces systolic blood pressure (SBP), alters histidine metabolism and exerts the antihypertensive effect via the central histamine H3 receptor in spontaneously hypertensive rats[3].

Animal Model:spontaneously hypertensive rats (SHR) [3]
Dosage:6.5? mg/kg
Administration:p.o., single dosage
Result:Reduced blood pressure and produced a change in metabolites.
Increased histidine levels after 1.5-3 h after administration.

References

[1] Kodera Y, et al. Chemical and Biological Properties of S-1-Propenyl-l-Cysteine in Aged Garlic Extract. Molecules. 2017 Mar 31;22(4). DOI:10.3390/molecules22040570
[2] Tsuneyoshi T, et al., S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells. Nitric Oxide. 2019 Mar 1;84:22-29. DOI:10.1016/j.niox.2019.01.003
[3] Matsutomo T, et al., Metabolomic study reveals the acute hypotensive effect of S-1-propenylcysteine accompanied by alteration of the plasma histidine level in spontaneously hypertensive rats. J Pharm Biomed Anal. 2019 May 10;168:148-154. DOI:10.1016/j.jpba.2019.01.043
[4] Suzuki JI, et al., Anti-inflammatory action of cysteine derivative S-1-propenylcysteine by inducing MyD88 degradation. Sci Rep. 2018 Sep 20;8(1):14148. DOI:10.1038/s41598-018-32431-0

S-1-Propenyl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

S-1-Propenyl-L-cysteine Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32275 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38664 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29772 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20026 58
18153089275 3032079623@qq.com China 22695 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 18215 58

View Lastest Price from S-1-Propenyl-L-cysteine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
S-1-Propenyl-L-cysteine pictures 2024-10-28 S-1-Propenyl-L-cysteine
52438-09-2
US $1110.00-1450.00 / mg 10g TargetMol Chemicals Inc.
S-1-Propenyl-L-cysteine S 1 Propenyl L cysteine,S1PropenylLcysteine L-Cysteine, S-1-propen-1-yl- 52438-09-2