S-1-Propenyl-L-cysteine
- CAS No.
- 52438-09-2
- Chemical Name:
- S-1-Propenyl-L-cysteine
- Synonyms
- S-1-Propenyl-L-cysteine;L-Cysteine, S-1-propen-1-yl-;S 1 Propenyl L cysteine,S1PropenylLcysteine
- CBNumber:
- CB38054529
- Molecular Formula:
- C6H11NO2S
- Molecular Weight:
- 161.22
- MDL Number:
- MFCD29919772
- MOL File:
- 52438-09-2.mol
S-1-Propenyl-L-cysteine Chemical Properties,Uses,Production
Uses
S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model[1]. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway[2]. S-1-Propenyl-L-cysteine is orally active.
in vivo
S-1-Propenyl-L-cysteine (6.5 mg/kg, p.o.) reduces systolic blood pressure (SBP), alters histidine metabolism and exerts the antihypertensive effect via the central histamine H3 receptor in spontaneously hypertensive rats[3].
Animal Model: | spontaneously hypertensive rats (SHR) [3] |
Dosage: | 6.5? mg/kg |
Administration: | p.o., single dosage |
Result: | Reduced blood pressure and produced a change in metabolites. Increased histidine levels after 1.5-3 h after administration. |
References
[1] Kodera Y, et al. Chemical and Biological Properties of S-1-Propenyl-l-Cysteine in Aged Garlic Extract. Molecules. 2017 Mar 31;22(4). DOI:10.3390/molecules22040570
[2] Tsuneyoshi T, et al., S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells. Nitric Oxide. 2019 Mar 1;84:22-29. DOI:10.1016/j.niox.2019.01.003
[3] Matsutomo T, et al., Metabolomic study reveals the acute hypotensive effect of S-1-propenylcysteine accompanied by alteration of the plasma histidine level in spontaneously hypertensive rats. J Pharm Biomed Anal. 2019 May 10;168:148-154. DOI:10.1016/j.jpba.2019.01.043
[4] Suzuki JI, et al., Anti-inflammatory action of cysteine derivative S-1-propenylcysteine by inducing MyD88 degradation. Sci Rep. 2018 Sep 20;8(1):14148. DOI:10.1038/s41598-018-32431-0
S-1-Propenyl-L-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
S-1-Propenyl-L-cysteine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32275 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29772 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 20026 | 58 |
18153089275 | 3032079623@qq.com | China | 22695 | 58 | |
Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 18215 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
TargetMol Chemicals Inc. | 58 |
58 | |
Adooq Bioscience LLC | 58 |
View Lastest Price from S-1-Propenyl-L-cysteine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-10-28 | S-1-Propenyl-L-cysteine
52438-09-2
|
US $1110.00-1450.00 / mg | 10g | TargetMol Chemicals Inc. |
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- S-1-Propenyl-L-cysteine
52438-09-2
- US $1110.00-1450.00 / mg
- TargetMol Chemicals Inc.