N(4)-methylcytidine
- CAS No.
- 10578-79-7
- Chemical Name:
- N(4)-methylcytidine
- Synonyms
- N4-Me-rC;Nsc518744;N4-Methyl-Cr;4-Methylcytidine;Cytidine, N-Methyl-;N(4)-methylcytidine;N4-Methylcytidine, RNA modified nucleoside m4C;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one
- CBNumber:
- CB21366945
- Molecular Formula:
- C10H15N3O5
- Molecular Weight:
- 257.24
- MDL Number:
- MFCD23701766
- MOL File:
- 10578-79-7.mol
- MSDS File:
- SDS
| Melting point | 202-203 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 504.2±60.0 °C(Predicted) |
| Density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 13.48±0.70(Predicted) |
| form | Solid |
| color | Off-White to Beige |
| Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H304-H413 |
| Precautionary statements | P501-P273-P331-P301+P310-P405 |
N(4)-methylcytidine price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B426568 | N4-Methylcytidine | 10578-79-7 | 5mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NM76577 | N4-Methylcytidine | 10578-79-7 | 25mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NM76577 | N4-Methylcytidine | 10578-79-7 | 50mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NM76577 | N4-Methylcytidine | 10578-79-7 | 100mg | $350 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | NUC0005217 | N4-METHYLCYTIDINE 95.00% | 10578-79-7 | 100MG | $407.4 | 2021-12-16 | Buy |
N(4)-methylcytidine Chemical Properties,Uses,Production
Description
N4-Methylcytidine is a nucleoside analogue that inhibits synthesis of human mitochondrial DNA by inhibiting bacterial enzyme uridine-cytidine kinase, which converts uridine to cytidine in the mitochondria. N4-Methylcytidine has been shown to be potent against viruses such as HIV and herpes simplex virus type 1 (HSV-1) in cell culture studies. This antiviral effect is due to the interference with viral dna replication and protein synthesis by preventing incorporation of uracil into dna and ribosomal RNA.
Uses
N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Definition
ChEBI: N4-Methylcytidine is a pyrimidine nucleoside.
References
[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
N(4)-methylcytidine Preparation Products And Raw materials
Raw materials
Preparation Products
N(4)-methylcytidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29856 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9642 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9985 | 58 |
| Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +86-18055311600 | sales1@nuowei-chem.com | China | 1627 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5997 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
View Lastest Price from N(4)-methylcytidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-01 | N4-Methylcytidine
10578-79-7
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2019-09-02 | N(4)-methylcytidine
10578-79-7
|
US $7.00 / KG | 1KG | 99% | JD 555 | Career Henan Chemical Co |
-
- N4-Methylcytidine
10578-79-7
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- N(4)-methylcytidine
10578-79-7
- US $7.00 / KG
- 99%
- Career Henan Chemical Co