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ChemicalBook >> CAS DataBase List >>sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide

CAS No.
865625-56-5
Chemical Name:
sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide
Synonyms
DF2156;DF 2156;DF2156A;DF-2156;DF-2156A;DF 2156A;sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide
CBNumber:
CB12598858
Molecular Formula:
C11H11F3NNaO6S2
Molecular Weight:
397.3231196
MDL Number:
MFCD22419381
MOL File:
865625-56-5.mol
Last updated:2025-04-17 18:22:24

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide Properties

storage temp. Store at -20°C
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L168750 LadarixinSodium 865625-56-5 10mg $450 2021-12-16 Buy
TRC L168750 LadarixinSodium 865625-56-5 25mg $960 2021-12-16 Buy
Product number Packaging Price Buy
L168750 10mg $450 Buy
L168750 25mg $960 Buy

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide Chemical Properties,Uses,Production

Uses

Ladarixin Sodium is a a dual CXCR1/2 inhibitor. It has therapeutic potential for treating type I diabetes and various melanoma.

in vivo

Ladarixin (10 mg/kg; p.o. once a day) reduces allergic airway inflammation in a model of single OVA exposure. Ladarixin reduces allergic airway inflammation, remodeling, and bronchial hyperreactivity in a model of chronic OVA exposure[1].
Ladarixin (10 mg/kg; p.o. once a day for 8 days) reduces pulmonary inflammation and fibrosis induced by bleomycin in mice[1].
Ladarixin (10 mg/kg; p.o. once a day for 3 days) protects mice from cigarette smoke-induced exacerbation of influenza-A infection[1].
Ladarixin is also effective in decreasing CXCL8-induced polymorphonuclear leukocyte infiltration in several animal models without a significant dose-related reduction in systemic neutrophil counts[2].

Animal Model:Mice (cigarette smoke-induced exacerbation of Influenza-A infection model)[1]
Dosage:10 mg/kg
Administration:P.o. once a day at days 2, 3 and 4 post-infection
Result:Significantly attenuated the exacerbation in lethality and respiratory changes noted in CSFlu group.

IC 50

CXCR1; CXCR2

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide Preparation Products And Raw materials

Raw materials

Preparation Products

sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32286 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19904 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 4998 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 21356 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12000 58

View Lastest Price from sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ladarixin Sodium pictures 2024-10-28 Ladarixin Sodium
865625-56-5
US $177.00-916.00 / mg 10g TargetMol Chemicals Inc.
sodiuM (R)-(Methylsulfonyl)(2-(4-(((trifluoroMethyl)sulfonyl)oxy)phenyl)propanoyl)aMide DF 2156 DF 2156A DF2156 DF-2156 DF2156A DF-2156A 865625-56-5