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ChemicalBook >> CAS DataBase List >>pacidamycin 1

pacidamycin 1

CAS No.
121264-05-9
Chemical Name:
pacidamycin 1
Synonyms
A68567;A 68567;A-68567;Pacidamycin I;pacidamycin 1;Butanamide, N-[[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]carbonyl]-L-alanyl-N3-(L-alanyl-3-hydroxy-L-phenylalanyl)-2-amino-N-[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]-3-(methylamino)-, (2S,3S)-
CBNumber:
CB11367394
Molecular Formula:
C41H50N10O12
Molecular Weight:
874.91
MDL Number:
MOL File:
121264-05-9.mol
Last updated:2025-04-18 09:51:38

pacidamycin 1 Properties

Density 1.463±0.06 g/cm3(Predicted)
pka 3.96±0.10(Predicted)

pacidamycin 1 Chemical Properties,Uses,Production

Description

Pacidamycin I is an antimicrobial nucleoside antibiotics that acts by inhibiting the clinically unexploited target translocase I, a key enzyme in peptidoglycan assembly. It is an essential pharmacophore isolated from Streptomyces coeruleorubidus.

Uses

Pacidamycin I (A-68567) is a nucleoside peptide antibiotic that is highly specific for Pseudomonas aeruginosa[1].

References

[1] Karwowski, et al. PACIDAMYCINS, A NOVEL SERIES OF ANTIBIOTICS WITH ANTl-PSEUDOMONAS AERUGINOSA ACTIVITY I. TAXONOMY OF THE PRODUCING ORGANISM AND FERMENTATION. The Journal of antibiotics 42.4 (1989): 506-511. DOI:10.7164/antibiotics.42.506

pacidamycin 1 Preparation Products And Raw materials

Raw materials

Preparation Products

pacidamycin 1 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19689 58
Zhejiang Huida Biotech Co., LTD 0571-89903882 15990081639 sunshixuan@huidabiotech.com China 3644 58
Zhejiang Huida Biotech Co., LTD 0571-0571-89903882 15990081639 sunshixuan@huidabiotech.com China 3705 58
pacidamycin 1 A 68567 A68567 A-68567 Pacidamycin I Butanamide, N-[[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]carbonyl]-L-alanyl-N3-(L-alanyl-3-hydroxy-L-phenylalanyl)-2-amino-N-[(Z)-[(4R,5R)-5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]-3-(methylamino)-, (2S,3S)- 121264-05-9