Veterinary Drugs and Treatments

Lodoxamine tromethamine is a mast cell stabilizer that inhibits Type I hypersensitivity responses by preventing antigen mediated histamine release. Lodoxamine stabilizes mast cells by blocking calcium influx into the cell upon antigen recognition, thereby blocking histamine release. Lodoxamine has no intrinsic vasoconstrictor, antihistaminic, cyclooxygenase inhibition or other anti-inflammatory properties. Lodoxamine is used in people for management of conjunctivitis associated with seasonal allergy and other histamine mediated disorders. In veterinary medicine, lodoxamine tromethamine has been used in horses and small animal patients with presumed allergic conjunctivitis.