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ChemicalBook >> CAS DataBase List >>4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

CAS No.
5623-18-7
Chemical Name:
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
Synonyms
Metfol-B;NSC 408937;Methotrexate-EP-Imp-D;N10-Methyl Pteroic Acid;Methotrexate EP Impurity D;Methotrexate Impurity 4(EP-D);Methotrexate Impurity 4（Methotrexate EP Impurity D）;Methotrexate EP Impurity D（Amethopterin EP Impurity D）;4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino}benzoic acid;p-[(2-Amino-4-hydroxy-6-pteridinyl)methyl(methyl)amino]benzoic acid
CBNumber:
CB02262484
Molecular Formula:
C15H14N6O3
Molecular Weight:
326.31
MDL Number:
MOL File:
5623-18-7.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Properties

Melting point >245°C (dec.)
Boiling point 583.7±60.0 °C(Predicted)
Density 1.58±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Aqueous Base (Slightly), DMSO (Very Slightly, Heated), Methanol (Very Slightly)
pka 4.74±0.10(Predicted)
color Orange to Red
FDA UNII 9RHB9JD89E
UNSPSC Code 41116107
NACRES NA.24

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M1000008 Methotrexate impurity D European Pharmacopoeia (EP) Reference Standard 5623-18-7 m1000008 $220 2024-03-01 Buy
TRC M326265 N10-MethylPteroicAcid 5623-18-7 250mg $810 2021-12-16 Buy
TRC M326265 N10-MethylPteroicAcid 5623-18-7 500mg $1455 2021-12-16 Buy
TRC M326265 N10-MethylPteroicAcid 5623-18-7 25mg $105 2021-12-16 Buy
Medical Isotopes, Inc. 60247 N10-MethylPteroicAcid 5623-18-7 500mg $2200 2021-12-16 Buy
Product number Packaging Price Buy
M1000008 m1000008 $220 Buy
M326265 250mg $810 Buy
M326265 500mg $1455 Buy
M326265 25mg $105 Buy
60247 500mg $2200 Buy

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Chemical Properties,Uses,Production

Chemical Properties

Dark Orange Solid

Uses

Methotrexate (M260675) impurity D.

Uses

N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.

150-13-0
5623-18-7
Synthesis of 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid from 4-Aminobenzoic acid

4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid Preparation Products And Raw materials

Global( 72)Suppliers
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Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9642 58
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China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 6335 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
QUALITY CONTROL SOLUTIONS LTD. 		0755-66853366; 13670046396 ORDERS@QCSRM.COM China 24342 58
J & K SCIENTIFIC LTD. 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
p-[(2-Amino-4-hydroxy-6-pteridinyl)methyl(methyl)amino]benzoic acid N10-Methyl Pteroic Acid 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]MethylaMino]benzoic Acid Metfol-B NSC 408937 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino}benzoic acid Methotrexate EP Impurity D Methotrexate Impurity 4(EP-D) Methotrexate EP Impurity D/N10-Methylpteroic acid/4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid Methotrexate EP Impurity D（Amethopterin EP Impurity D） Methotrexate-EP-Imp-D 4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl](methyl)amino}benzoic acid Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]- Methotrexate Impurity 4（Methotrexate EP Impurity D） 4-(((2-Amino-4-oxo-4,8-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid (Methotrexate Impurity) 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid 5623-18-7 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals