1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
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- CAS號(hào):
- 157124-84-0
- 英文名:
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 英文別名:
- BPH-652;BPH 652,BPH652;FIOQVVKPUBNHEM-UHFFFAOYSA-N;1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 中文名:
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
- 中文別名:
- 化合物 T10587;化合物 BPH-652
- CBNumber:
- CB62609504
- 分子式:
- C16H16K3O7PS
- 分子量:
- 500.627701
- MOL File:
- 157124-84-0.mol
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1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt化學(xué)性質(zhì)
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儲(chǔ)存條件:
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4°C, away from moisture
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形態(tài):
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Solid
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顏色:
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White to off-white
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水溶解性:
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Water : 25 mg/mL (49.94 mM; Need ultrasonic)
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1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt性質(zhì)、用途與生產(chǎn)工藝
BPH-652 是 CrtM 的抑制劑，Ki 值為 1.5 nM，IC50 值為100-300 nM (S. aureus 色素形成)。
Ki: 1.5 nM (CrtM).
IC50: 100-300 nM (
S. aureus
pigment formation).
BPH-652 treatment (0.5 mg twice per day (days ?1, 0, 1, and 2), Intraperitoneal injection) significantly lowers
S. aureus
bacterial counts in the kidneys of the mice than those of the control group (P < 0.001), with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group.
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Animal Model:
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A systemic
S. aureus
infection model in mice.
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Dosage:
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0.5 mg twice per day (days ?1, 0, 1, and 2).
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Administration:
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Intraperitoneal injection.
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Result:
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S. aureus
bacterial counts in the kidneys of the mice treated with BPH-652 were significantly lower than those of the control group.
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1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS編號(hào) | 包裝 | 價(jià)格 |
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| 2025/02/05 | HY-16115 | BPH-652 | 157124-84-0 | 1 mg | 3400元 |
| 2024/08/19 | HY-16115 | 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
BPH-652 | 157124-84-0 | 5mg | 8500元 |
1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt
生產(chǎn)廠(chǎng)家
157124-84-0, 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt 相關(guān)搜索:
- 抑制劑
- 化合物 BPH-652
- 化合物 T10587
- 157124-84-0
- BPH 652,BPH652
- FIOQVVKPUBNHEM-UHFFFAOYSA-N
- BPH-652
- 1-phosphono-4-(3-phenoxyphenyl) butylsulfonic acid tripotassiuM salt