（S）FTY720磷酸鹽
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- CAS號(hào):
- 402616-26-6
- 英文名:
- (S) FTY720 PHOSPHATE
- 英文別名:
- (S)-FTY720-;(S)-FTY720-P;FTY720 (S)-Phosphate;(S) FTY720 PHOSPHATE;FTY720 (S) Phosphate,FTY720 (S)Phosphate,FTY-720 (S)-Phosphate;(S)-2-Amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl dihydrogen phosphate;(2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol);1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1-(dihydrogen phosphate), (2S)-;2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester
- 中文名:
- （S）FTY720磷酸鹽
- 中文別名:
- 化合物 T15354;(S)FTY720磷酸鹽;S) FTY720磷酸酯;FTY720(S)-磷酸鹽;化合物 FTY720 (S)-PHOSPHATE;(S)FTY720磷酸鹽/FTY720(S)-磷酸鹽;(S)-2-氨基-2-(羥甲基)-4-(4-辛基苯基)丁基二氫磷酸酯
- CBNumber:
- CB4988579
- 分子式:
- C19H34NO5P
- 分子量:
- 387.45
- MOL File:
- 402616-26-6.mol
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（S）FTY720磷酸鹽化學(xué)性質(zhì)
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熔點(diǎn):
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184-186°C
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沸點(diǎn):
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584.2±60.0 °C(Predicted)
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密度:
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1.172±0.06 g/cm3(Predicted)
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儲(chǔ)存條件:
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-20°C Freezer
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溶解度:
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DMSO: soluble0.3mg/mL, clear (warmed)
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酸度系數(shù)(pKa):
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1.73±0.10(Predicted)
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形態(tài):
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Solid
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顏色:
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white to beige
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（S）FTY720磷酸鹽性質(zhì)、用途與生產(chǎn)工藝
FTY720 (S)-Phosphate 是一種 S1P 受體 1 (S1PR1) 激動(dòng)劑，可以用于急性肺損傷等急性炎癥的研究。
FTY720 (S)-Phosphate is an agonist of S1PR1. FTY720 (S)-Phosphate (Tys, 1 μM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1, but shows no effect on inducing ubiquitination of S1PR1. FTY720 (S)-Phosphate (0.01-50 μM) also reduces β-arrestin recruitment to S1PR1.
FTY720 (S)-Phosphate (0.5 mg/kg, i.p.) preserves S1PR1 expression in mouse lungs, is protective in bleomycin-induced acute lung injury (ALI) and attenuates lung tissue leukocyte infiltration in bleomycin-injured mice.
（S）FTY720磷酸鹽
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS編號(hào) | 包裝 | 價(jià)格 |
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| 2024/11/08 | HY-15382 | FTY720 (S)-Phosphate | | 1 mg | 2080元 |
| 2024/11/08 | HY-15382 | （S）FTY720磷酸鹽
FTY720 (S)-Phosphate | 402616-26-6 | 5mg | 5200元 |
402616-26-6, （S）FTY720磷酸鹽 相關(guān)搜索:
- Metabolites & Impurities
- Inhibitors
- All Inhibitors
- 抑制劑
- 試劑盒-細(xì)胞分析試劑盒
- (S)FTY720磷酸鹽/FTY720(S)-磷酸鹽
- 化合物 FTY720 (S)-PHOSPHATE
- (S)-2-氨基-2-(羥甲基)-4-(4-辛基苯基)丁基二氫磷酸酯
- 化合物 T15354
- FTY720(S)-磷酸鹽
- (S)FTY720磷酸鹽
- S) FTY720磷酸酯
- 402616-26-6
- (S)-2-Amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl dihydrogen phosphate
- FTY720 (S) Phosphate,FTY720 (S)Phosphate,FTY-720 (S)-Phosphate
- 1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1-(dihydrogen phosphate), (2S)-
- (S)-FTY720-P
- 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester
- (S)-FTY720-
- (2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol)
- FTY720 (S)-Phosphate
- (S) FTY720 PHOSPHATE