特戊酸氟米松
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- CAS號:
- 2002-29-1
- 英文名:
- Flumethasone 21-pivalate
- 英文別名:
- Losalen;Lorinden;locorten;locacorten;NSC 107680;21-pivalate;FLUMETHSONEPIVALATE;FLUMETHASONE PIVALATE;Flumethasome pivalate;flumetasone 21-pivalate
- 中文名:
- 特戊酸氟米松
- 中文別名:
- 戊酸氟米松;新戊酸氯米松;特戊酸氟米松;新戊酸氟米松;氟米松特戊酸;氟米松特戊酸酯;雙氟美松叔戊酸酯;特戊酸氟米松 標準品;氟米松 21-戊酸酯;化合物 T20802
- CBNumber:
- CB4762018
- 分子式:
- C27H36F2O6
- 分子量:
- 494.57
- MOL File:
- 2002-29-1.mol
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特戊酸氟米松化學性質
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熔點:
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>263°C (dec.)
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沸點:
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600.3±55.0 °C(Predicted)
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密度:
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1.27±0.1 g/cm3(Predicted)
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儲存條件:
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Refrigerator
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溶解度:
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dioxane: soluble4.0ML, clear, colorless to very faintly yellow (50 mg + 4.0 mL dioxane)
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形態(tài):
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solid
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酸度系數(shù)(pKa):
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11.86±0.70(Predicted)
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顏色:
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White to Off-White
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旋光性 (optical activity):
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[α]25/D 71.0 to 82.0°, c = 1 in dioxane
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CAS 數(shù)據(jù)庫:
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2002-29-1(CAS DataBase Reference)
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EPA化學物質信息:
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Flumethasone-21-pivalate (2002-29-1)
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特戊酸氟米松性質、用途與生產(chǎn)工藝
特戊酸氟米松，又叫新戊酸氟米松，是一種皮質激素消炎藥物。皮質激素（GC）是機體內極為重要的一類調節(jié)分子，它對機體的發(fā)育、生長、代謝以及免疫功能等起著重要調節(jié)作用，是機體應激反應最重要的調節(jié)激素，也是臨床上使用最為廣泛而有效的抗炎和免疫抑制劑。
四取代的嘧啶并嘧啶例如雙嘧達莫(也稱為2，6-二(二乙醇氨基)-4，8-二哌啶基嘧啶并(5，4-d)嘧啶)與皮質類固醇或潑尼松龍(也稱為1-脫氫皮質醇、1-脫氫氫化可的松、1，4-孕甾二烯(pregnadiene)-11-β，17-α，21-三醇-3，20-二酮、以及11-β，17-α，21-三羥基-1，4-孕甾二烯-3，20-二酮)的組合，導致顯著抑制外周血單核細胞(PBMC)中誘導的TNFα水平。
特戊酸氟米松
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
2002-29-1, 特戊酸氟米松 相關搜索:
- Organics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Steroids
- 抑制劑
- 原料
- 甾體激素類
- Antibiotics A to Z
- Antibiotics A-F
- Antibiotics
- BioChemical
- C27H36F2O6
- 特戊酸氟米松,10 MM DMSO 溶液
- 新戊酸氟米松, 糖皮質激素受體激動劑
- 特戊酸氟米松/A1A
- 氟米松特戊酸酯
- 氟米松特戊酸
- 氟米松雜質13(特戊酸氟米松)
- 新戊酸氯米松
- 氟米松 21-戊酸酯
- 化合物 T20802
- 氟米松特戊酸 EP標準品
- 雙氟美松叔戊酸酯 USP標準品
- 戊酸氟米松
- 特戊酸氟米松 標準品
- 雙氟美松叔戊酸酯
- 特戊酸氟米松
- 新戊酸氟米松
- 2002-29-1
- Flumethasone pivalate, 10 mM in DMSO
- Flumethasone Impurity 13(Flumethasone 21-Pivalate)
- Flumethasone Pivalate (1274006)
- Flumetasone pivalate CRS
- FluMethasone pivalate USP
- (6α,11β,16α)-21-(2,2-DiMethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-Methyl-pregna-1,4-diene-3,20-dione
- FLUMETHSONEPIVALATE
- Flumethasone Pivalate (200 mg)
- Flumethasome pivalate
- flumetasone 21-pivalate
- pregna-1,4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,17,21-trihydroxy-16-alp
- locorten
- Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl-, 21-pivalate (7CI, 8CI)
- Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6α,11β,16α)-
- Pivalic acid, 21-ester with 6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (8CI)
- NSC 107680
- Losalen
- Lorinden
- 6α,9α-Difluoro-16α-methylprednisolone 21-pivalate
- 6α,9α-Difluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-pivalate
- 6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate)
- Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-
- 6ALPHA,9-DIFLUORO-11BETA,17,21-TRIHYDROXY-16ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-[2,2-DIMETHYLPROPIONATE]
- 6a,9a-difluoro-16a-methyl-prednisolone-21-pivalate
- FLUMETHASONE PIVALATE
- flumethasone 21-pivalate
- locacorten
- 21-pivalate