TNG348
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- CAS號(hào):
- 2839740-79-1
- 英文名:
- 2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)-7-(2,2,2-trifluoroethyl)-7,9-dihydro-8H-purin-8-imine
- 英文別名:
- 2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)-7-(2,2,2-trifluoroethyl)-7,9-dihydro-8H-purin-8-imine;8H-Purin-8-imine, 2-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-7-(2,2,2-trifluoroethyl)-
- 中文名:
- TNG348
- 中文別名:
- TNG348;2-(4-環(huán)丙基-6-甲氧基嘧啶-5-基)-9-(4-(1-甲基-4-(三氟甲基)-1H-咪唑-2-基)芐基)-7-(2,2,2-三氟乙基)-7,9-二氫-8H-嘌呤-8-亞胺
- CBNumber:
- CB313929108
- 分子式:
- C27H23F6N9O
- 分子量:
- 603.52
- MOL File:
- 2839740-79-1.mol
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TNG348化學(xué)性質(zhì)
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沸點(diǎn):
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641.3±65.0 °C(predicted)
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密度:
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1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
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酸度系數(shù)(pKa):
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2.60±0.60(predicted)
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形態(tài):
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Solid
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顏色:
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White to light yellow
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TNG348性質(zhì)、用途與生產(chǎn)工藝
TNG348 是一種具有口服活性的去泛素化酶 USP1 抑制劑，可用于在 BRCA1/2 突變或 HRD+ 癌癥中的研究。
TNG348
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
2839740-79-1, TNG348 相關(guān)搜索:
- 2-(4-環(huán)丙基-6-甲氧基嘧啶-5-基)-9-(4-(1-甲基-4-(三氟甲基)-1H-咪唑-2-基)芐基)-7-(2,2,2-三氟乙基)-7,9-二氫-8H-嘌呤-8-亞胺
- TNG348
- 2839740-79-1
- 8H-Purin-8-imine, 2-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-7,9-dihydro-9-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]-7-(2,2,2-trifluoroethyl)-
- 2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzyl)-7-(2,2,2-trifluoroethyl)-7,9-dihydro-8H-purin-8-imine