CCMI
|
|
|
- CAS號(hào):
- 917837-54-8
- 英文名:
- [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
- 英文別名:
- CCMI;AVL-3288;AVL-3288 (CCMI);CCMI, 10 mM in DMSO;N-(4-Chlorophenyl)-3-((4-chlorophenyl)amino)-2-(3-methylisoxazol-5-yl)acrylamide;N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide;(E)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide;[N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide;5-IsoxazoleacetaMide, N-(4-chlorophenyl)-α-[[(4-chlorophenyl)aMino]Methylene]-3-Methyl-;N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide
- 中文名:
- CCMI
- 中文別名:
- 化合物CCMI;CCMI,Α7NACHRS的正變構(gòu)調(diào)節(jié)劑;化合物CCMI,10 MM DMSO 溶液;N-(4-氯苯基)-3-((4-氯苯基)氨基)-2-(3-甲基異惡唑-5-基)丙烯酰胺
- CBNumber:
- CB12518975
- 分子式:
- C19H15Cl2N3O2
- 分子量:
- 388.25
- MOL File:
- 917837-54-8.mol
|
|
|
CCMI化學(xué)性質(zhì)
-
沸點(diǎn):
-
605.4±55.0 °C(Predicted)
-
|
-
密度:
-
1.412±0.06 g/cm3(Predicted)
-
|
-
儲(chǔ)存條件:
-
Keep in dark place,Sealed in dry,2-8°C
-
|
-
溶解度:
-
DMSO (Slightly), Methanol (Very Slightly)
-
|
-
形態(tài):
-
Solid
-
|
-
酸度系數(shù)(pKa):
-
10.37±0.70(Predicted)
-
|
-
顏色:
-
Off-White to Pale Yellow
-
|
CCMI性質(zhì)、用途與生產(chǎn)工藝
CCMI 是一種有效、選擇性的 α7 nAChR 正向別構(gòu)調(diào)節(jié)劑，不是通過正性結(jié)合位點(diǎn)與 α7 nAChR 結(jié)合并使其激活，能有效正向調(diào)節(jié) α7 nAChR 上激動(dòng)劑誘導(dǎo)的電流。CCMI 在神經(jīng)系統(tǒng)認(rèn)知功能紊亂疾病中具有潛在療效。
CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
CCMI
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2025/02/08 | HY-12150 | CCMI
CCMI | 917837-54-8 | 10mM * 1mLin DMSO | 530元 |
| 2025/02/08 | HY-12150 | CCMI
CCMI | 917837-54-8 | 5mg | 620元 |
917837-54-8, CCMI 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- 化合物CCMI,10 MM DMSO 溶液
- CCMI,Α7NACHRS的正變構(gòu)調(diào)節(jié)劑
- 化合物CCMI
- N-(4-氯苯基)-3-((4-氯苯基)氨基)-2-(3-甲基異惡唑-5-基)丙烯酰胺
- 917837-54-8
- CCMI, 10 mM in DMSO
- N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide
- Inhibitor,AVL 3288,inhibit,UCI 4083,Nicotinic acetylcholine receptors,CCMI,nAChR,AVL3288,UCI4083,UCI-4083
- AVL-3288 (CCMI)
- N-(4-Chlorophenyl)-3-((4-chlorophenyl)amino)-2-(3-methylisoxazol-5-yl)acrylamide
- N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide
- AVL-3288
- (E)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide
- 5-IsoxazoleacetaMide, N-(4-chlorophenyl)-α-[[(4-chlorophenyl)aMino]Methylene]-3-Methyl-
- CCMI
- [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide