916898-61-8
中文名稱
化合物 T26834
英文名稱
Butanoic acid, 4-amino-, 2-[4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl ester, methanesulfonate (1:3)
CAS
916898-61-8
分子式
C26H37ClN4O5S2
分子量
585.18
MOL 文件
916898-61-8.mol
916898-61-8 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26834 英文別名
CYP-1020BL-1020 Mesylate
Perphenazine GABA ester
Butanoic acid, 4-amino-, 2-[4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl ester, methanesulfonate (1:3)
應(yīng)用領(lǐng)域
用途一
BL-1020, also known as CYP-1020; AN-168, a GABA A receptor agonist and dopamine receptor antagonist potentially for the treatment of schizophrenia, BL-1020 is an ester of GABA and perphenazine, and pharmacologically it acts as a D2 antagonist and GABA agonist. It has shown pro-cognitive effects in the trials. In March 2013, it went into the II/III trial phase. It has been introduced by BioLineRx, a biopharmaceutical development company.