76123-41-6
中文名稱(chēng)
化合物 T32026
英文名稱(chēng)
GYKI 13324
CAS
76123-41-6
分子式
C10H18Cl2N6O6
分子量
389.19
MOL 文件
76123-41-6.mol
76123-41-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 T32026 英文別名
GYKI 133241-(2-chloroethyl)-3-[4-[2-chloroethylcarbamoyl(nitroso)amino]-2,3-dihydroxybutyl]-1-nitrosourea
應(yīng)用領(lǐng)域
用途一
GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. GYKI-13324 was studied on human colorectal tumor xenograft lines. Given orally in single or multiple daily doses, GYKI-13324 produced long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, with slightly lower toxicity than that of BCNU, seems to be a candidate in the clinical management of colorectal tumors.