71002-09-0
71002-09-0 結構式
基本信息
中文別名
吡拉唑酸 英文別名
ZK-76604pirazolac
4-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-acetic acid
1-(4-Fluorophenyl)-4-(4-chlorophenyl)-1H-pyrazole-3-acetic acid
1H-Pyrazole-3-acetic acid, 4-(4-chlorophenyl)-1-(4-fluorophenyl)-
物理化學性質
熔點148-149°; mp 135-136°
沸點520.8±50.0 °C(Predicted)
密度1.36±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)3.94±0.10(Predicted)
常見問題列表
生物活性
Pirazolac 是一種非甾體抗炎藥。體外研究
Pirazolac is a non-steroidal anti-inflammatory drug. Pirazolac concentration-relatedly inhibits the accumulation of prostanoids in incubates of human gastric mucosa, but this inhibition is less than that by indomethacin and other commonly used non-steroidal anti-inflammatory drugs. This difference may explain the claim that Pirazolac is less damaging to the stomach.