70-09-7
中文名稱(chēng)
2-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺
英文名稱(chēng)
NSC 38280
CAS
70-09-7
MOL 文件
70-09-7.mol
更新日期
2024/12/15 19:35:15
70-09-7 結(jié)構(gòu)式
基本信息
中文別名
化合物NSC-603392-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺
英文別名
WanderHr 2198
Nsc 60339
NSC 38280
2-Chloro-4',4''-di-2-imidazolin-2-yl-terephthalanilide
inhibit,NSC 60339,NSC60339,NSC-60339,Bacterial,Inhibitor
2-Chloro-N,N'-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide
Terephthalanilide, 2-chloro-4',4''-di-2-imidazolin-2-yl- (8ci)
2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide
1,4-Benzenedicarboxamide, 2-chloro-N,N'-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)- (9ci)
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: 5 mg/mL (10.27 mM)
形態(tài)Solid
顏色Off-white to light yellow
2-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/02/08 | HY-119172 | 2-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺 NSC-60339 | 70-09-7 | 1 mg | 803元 |
| 2025/02/08 | HY-119172 | 2-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺 NSC-60339 | 70-09-7 | 5mg | 1988元 |
| 2025/02/08 | HY-119172 | 2-氯-N1,N4-雙(4-(4,5-二氫-1H-咪唑-2-基)苯基)對(duì)苯二甲酰胺 NSC-60339 | 70-09-7 | 10mg | 2913元 |
常見(jiàn)問(wèn)題列表
生物活性
NSC-60339 是外排泵的抑制劑和 AcrAB-TolC 的底物，是聚對(duì)苯二甲酸衍生物，是一種潛在的癌癥化療化合物。體外研究
NSC 60339 has been correlated with the sensitivity, resistance, or cross-resistance of 7 tumor lines to phthalanilide treatment in vivo. The sensitive tumors (L1210, L1210/MTX, L1210/ara-C, and P815) rapidly takes up the drug and retained it primarily as lipid-bound drug for the 24-hr experimental period. The resistant tumor, L1210/NSC 60339, and 2 cross-resistant tumors, P388/VCR and P815/VLB, took up as much drug as the sensitive tumors did by 0.5 hr, but there was an efflux of lipid-bound drug from these resistant tumors by 24 hr.