41544-24-5
中文名稱
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
英文名稱
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
CAS
41544-24-5
分子式
C16H28N2O2.ClH
分子量
316.867
MOL 文件
41544-24-5.mol
41544-24-5 結(jié)構(gòu)式
基本信息
中文別名
鹽酸曲金剛胺 英文別名
VirumerzViruserol
Viru-merz
Einecs 255-434-5
Tromantadine HCl
Tromantadin hydrochlorid
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
常見問題列表
生物活性
Tromantadine hydrochloride，Amantadine 衍生物，具有抗皰疹活性，可抑制單純皰疹病毒1型 (HSV-1) 和 HSV-2 的復(fù)制。靶點(diǎn)
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HSV-1
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HSV-2
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體外研究
Treatment of the cells with 10 to 50μg of Tromantadine reduces HSV-induced cytopathic effect. Treatment with 100 to 500μg of Tromantadine inhibits herpes simplex virus-induced cytopathic effect and reduces virus production. Complete inhibition of virus production is observed with treatments of 500μg to 1 mg. The antiherpetic activity of Tromantadine is dependent upon the viral inoculum size and the time of addition of the compound with respect to infection.