2206736-04-9
中文名稱
MRTX-1257
英文名稱
2-((S)-1-acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
CAS
2206736-04-9
分子式
C33H39N7O2
分子量
565.71
MOL 文件
2206736-04-9.mol
更新日期
2025/02/07 14:28:46
2206736-04-9 結(jié)構(gòu)式
基本信息
中文別名
化合物MRTX-1257(2S)-1-(1-氧代-2-丙烯-1-基)-4-[5,6,7,8-四氫-7-(8-甲基-1-萘基)-2-[[(2S)-1-甲基-2-吡咯烷基]甲氧基]吡啶并[3,4-D]嘧啶-4-基]-2-哌嗪乙腈
英文別名
MRTX-12572-((S)-1-ACRYLOYL-4-(7-(8-METHYLNAPHTHALEN-1-YL)-2-(((S)-1-METHYLPYRROLIDIN-2-YL)METHOXY)-5,6,7,8-TE
2-((2S)-1-acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-((1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
2-((S)-1-acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
2-[(2S)-4-[7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-prop-2-enoylpiperazin-2-yl]acetonitrile
2-Piperazineacetonitrile, 1-(1-oxo-2-propen-1-yl)-4-[5,6,7,8-tetrahydro-7-(8-methyl-1-naphthalenyl)-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-, (2S)-
所屬類別
有機(jī)原料：雜環(huán)化合物物理化學(xué)性質(zhì)
沸點(diǎn)845.5±75.0 °C(Predicted)
密度1?+-.0.06 g/cm3(Predicted)
儲(chǔ)存條件Store at -20°C, stored under nitrogen
溶解度DMSO : 55 mg/mL (97.22 mM; Need ultrasonic)
酸度系數(shù)(pKa)9.31±0.40(Predicted)
形態(tài)結(jié)晶固體
顏色Off-white to pink
