2121530-37-6
中文名稱
4-Hydroxy 4-Dedimethylamino Afatinib
英文名稱
4-Hydroxy 4-Dedimethylamino Afatinib
CAS
2121530-37-6
分子式
C22H20ClFN4O4
分子量
458.87
MOL 文件
2121530-37-6.mol
更新日期
2025/03/03 17:27:11
2121530-37-6 結(jié)構(gòu)式
基本信息
中文別名
馬來(lái)酸阿法替尼雜質(zhì)3 英文別名
Afatinib 4-Hydroxy AnalogAfatinib Maleate Acid Impurity 3
4-Hydroxy 4-Dedimethylamino Afatinib
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-
(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide
Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
應(yīng)用領(lǐng)域
用途一
(2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide is an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.