1984-94-7
1984-94-7 結(jié)構(gòu)式
基本信息
中文別名
磺胺均三嗪 英文別名
Sulfasymazine4-amino-N-(4,6-diethyl-s-triazin-2-yl)benzenesulfonamide
4-amino-N-(4,6-diethyl-1,3,5-triazin-2-yl)benzenesulfonamide
4-azanyl-N-(4,6-diethyl-1,3,5-triazin-2-yl)benzenesulfonamide
Benzenesulfonamide, 4-amino-N-(4,6-diethyl-1,3,5-triazin-2-yl)-
物理化學性質(zhì)
熔點186.5-187.5° (Taft); 190-190.5° (Bader)
沸點573.8±52.0 °C(Predicted)
密度1.359±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)pKa (30% acetone) = 5.4(at 25℃)
常見問題列表
生物活性
Sulfasymazine 是一種磺酰胺類藥物，表現(xiàn)出抗菌特性。靶點
Bacterial
體內(nèi)研究
Sulfasymazine is a sulfonamide drug and displays antibacterial properties. On a dosage basis, Sulfasymazine is from 2 to 10 times more potent than sulfisoxazole; on a blood level basis, Sulfasymazine potency ranges from 0.3 to 1. In acute toxicity studies in mice, the sodium salt of Sulfasymazine is tolerated at 2000 mg/kg orally, and at 1000 mg/kg intraperitoneally.