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1621585-17-8

中文名稱 Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-
英文名稱 Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-
CAS 1621585-17-8
分子式 C18H19F2N3O2S
分子量 379.42
MOL 文件 1621585-17-8.mol
1621585-17-8 結(jié)構(gòu)式 1621585-17-8 結(jié)構(gòu)式

基本信息

中文別名
化合物 T28390
英文別名
PF9238
PF-9238
PF 9238
PF-06649283 >=98% (HPLC)
Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-, (4R,4aR,6R,8aS)-

應(yīng)用領(lǐng)域

用途一
PF9238 is a beta-secretase I inhibitor. Treatment with PF9238 results in the accumulation of autofluorescent granules in the retinas. PF9238 has a CatD potency of 12 uM in vivo.
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