1613509-49-1
中文名稱
2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮
英文名稱
Pyrimido[4,5-b]quinoline-4,5(3H,10H)-dione, 2-cyclobutyl-10-methyl-3-phenyl-
CAS
1613509-49-1
分子式
C22H19N3O2
分子量
357.41
MOL 文件
1613509-49-1.mol
1613509-49-1 結(jié)構(gòu)式
基本信息
中文別名
2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮 英文別名
Pyrimido[4,5-b]quinoline-4,5(3H,10H)-dione, 2-cyclobutyl-10-methyl-3-phenyl-物理化學(xué)性質(zhì)
沸點495.3±55.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
儲存條件-10 to -25°C
溶解度DMSO: 2mg/mL, clear (Warmed)
酸度系數(shù)(pKa)2.41±0.20(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
應(yīng)用領(lǐng)域
用途一
SRI-41315 is a small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion. SRI-41315 induce a prolonged pause at stop codons and suppress PTCs associated with cystic fibrosis in immortalized and primary human bronchial epithelial cells, restoring CFTR expression and function. SRI-41315 suppresses PTCs by reducing the abundance of the termination factor eRF1. SRI-41315 also potentiates aminoglycoside-mediated readthrough, leading to synergistic increases in CFTR activity.2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-150090 | 2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮 SRI-41315 | 1613509-49-1 | 1 mg | 500元 |
| 2025/02/08 | HY-150090 | 2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮 SRI-41315 | 1613509-49-1 | 10 mM * 1 mLin DMSO | 865元 |
| 2025/02/08 | HY-150090 | 2-環(huán)丁基-10-甲基-3-苯基嘧啶并[4,5-B]喹啉-4,5(3H,10H)-二酮 SRI-41315 | 1613509-49-1 | 5 mg | 1100元 |