1567836-15-0
中文名稱
化合物 T27077
英文名稱
Glycine, N,N'-1,4-naphthalenediylbis[N-[(4-methoxyphenyl)sulfonyl]-
CAS
1567836-15-0
分子式
C28H26N2O10S2
分子量
614.64
MOL 文件
1567836-15-0.mol
1567836-15-0 結(jié)構(gòu)式
基本信息
中文別名
化合物 T27077 英文別名
CPUY192018CPUY192018 Na2
CPUY192018disodium
CPUY192018-disodium
CPUY192018 Disodium
Glycine, N,N'-1,4-naphthalenediylbis[N-[(4-methoxyphenyl)sulfonyl]-
物理化學性質(zhì)
沸點881.9±75.0 °C(Predicted)
密度1.502±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)3.10±0.30(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
CPUY192018 Disodium is a potent small-molecule inhibitor of the Keap1-Nrf2 PPI. CPUY192018 Disodium has a cytoprotective effect against DSS in both NCM460 cells and mouse colon via the activation of Nrf2 signaling. Activation of Nrf2 by directly inhibiting the Keap1-Nrf2 PPI may be beneficial as a treatment for ulcerative colitis.