115453-99-1
115453-99-1 結(jié)構(gòu)式
基本信息
中文別名
6-(4-氨基苯乙烯基)吡啶-2-羧酸 英文別名
CB-7921220CB-7921220 (CB7921220)
6-(4-Aminostyryl)picolinic acid
2-Pyridinecarboxylic acid, 6-[2-(4-aminophenyl)ethenyl]-
物理化學(xué)性質(zhì)
熔點(diǎn)225-226 °C
沸點(diǎn)504.3±50.0 °C(Predicted)
密度1.329±0.06 g/cm3(Predicted)
儲(chǔ)存條件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 0.3 mg/ml
酸度系數(shù)(pKa)1.01±0.50(Predicted)
形態(tài)A crystalline solid
顏色Pink to red
115453-99-1價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 2mg | 500元 |
| 2024/11/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 10mM * 1mLin DMSO | 661元 |
| 2024/11/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 5mg | 990元 |
常見問題列表
生物活性
CB-7921220是腺苷酸環(huán)化酶 (adenylate cyclase) 的抑制劑。體外研究
CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6.