| Identification | Back Directory | [Name]
Ac-DNLD-AMC | [CAS]
958001-92-8 | [Synonyms]
Ac-DNLD-AMC
AC-DNLD-AMC;CASPASE-3 SUBSTRATE;AC-ASP-ASN-LEU-ASP-MCA
L-α-Asparagine, N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C30H38N6O12 | [MDL Number]
MFCD07368596 | [MOL File]
958001-92-8.mol | [Molecular Weight]
674.66 |
| Chemical Properties | Back Directory | [Boiling point ]
1211.3±65.0 °C(Predicted) | [density ]
1.402±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Formic Acid: 1 mg/ml | [form ]
A lyophilized powder | [pka]
4.09±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively. |
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