Chemical Properties | Back Directory | [Boiling point ]
643.7±55.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 250 mg/mL (530.12 mM) | [form ]
Solid | [pka]
16.04±0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1]. | [IC 50]
CCR8: 11-87 nM (EC50) | [storage]
Store at -20°C | [References]
[1] Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72(2):327-40. DOI:10.1124/mol.106.035543 |
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MedChemExpress
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