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ChemicalBook--->CAS DataBase List--->950195-51-4

950195-51-4

950195-51-4 Structure

950195-51-4 Structure
IdentificationBack Directory
[Name]

LMD-009
[CAS]

950195-51-4
[Synonyms]

LMD-009
LMD 009;LMD009
[Molecular Formula]

C29H33N3O3
[MDL Number]

MFCD32201054
[MOL File]

950195-51-4.mol
[Molecular Weight]

471.59
Chemical PropertiesBack Directory
[Boiling point ]

643.7±55.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 250 mg/mL (530.12 mM)
[form ]

Solid
[pka]

16.04±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1].
[IC 50]

CCR8: 11-87 nM (EC50)
[storage]

Store at -20°C
[References]

[1] Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72(2):327-40. DOI:10.1124/mol.106.035543
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