| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
phosphate buffer: 1mg/mL, clear to slightly hazy (0.01 M phosphate buffer, 0.0027 M potassium chloride and 0.137 M sodium chloride, pH 7.4, at 25 °C) | [form ]
Solid | [color ]
Off-white to pink | [biological source]
human milk | [Water Solubility ]
H2O: soluble 5mg/mL |
| Hazard Information | Back Directory | [Uses]
Lactoferrin was used to grow Streptococcus mutans in an iron-limiting medium. It was used to test if lactoferrin impedes epithelial cell adhesion in vitro. It was also used to test the diagnostic value of blood cytokine concentrations in acute pneumonia. | [Biological Activity]
Lactoferrin is blood-brain barrier (BBB) traversable and has therapeutic potential to regulate inflammationimmunity and apoptosis in Parkinsonμs disease. It promotes the expression of brain-derived neurotrophic factor (BDNF) via various signaling pathways and aids protection in motor dysfunction. Lactoferrin favors osteogenic differentiation and proliferation of human adipose-derived stem cells (hADSCs). It exhibits proteolytic activity on Haemophilus influenzae colonization factors. Lactoferrin is also a nutraceutical and a potential marker in the pathophysiology of inflammatory bowel diseasesleukocytes''Lactoferrin is an iron binding protein. It is structurally similar to transferrinthe plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). |
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