Identification | Back Directory | [Name]
CARNITINE ACETYLTRANSFERASE | [CAS]
9029-90-7 | [Synonyms]
CrAT EC 2.3.1.7 Carnitine acetylase Acetylcarnitine transferase CARNITINE ACETYLTRANSFERASE Acetyltransferase, carnitine Carnitine-acetyl-CoA transferase Carnitine acetyl coenzyme A transferase Native Pigeon Carnitine Acetyltransferase ACETYL-CO-A: CARNITINE-O-ACETYLTRANSFERASE Acetyl-Co-A:carnitine-O-acetyltransferase, CrAT Carnitine Acetyltransferase pigeon breast muscle CARNITINE ACETYLTRANSFERASEFROM PIGEON B REAST MUSC carnitine acetyltransferase from pigeon breast muscle carnitine acetyltransferase from pigeon breast M.,~100 U/mg Carnitine Acetyltransferase from pigeon breast muscle, ≥50 units/mg protein | [EINECS(EC#)]
232-854-7 | [MDL Number]
MFCD00130725 |
Hazard Information | Back Directory | [General Description]
Carnitine acetyltransferase is a mitochondrial enzyme essential for fuel utilization. It is present in the mitochondrial matrix and peroxisome. It is involved in the fatty acid metabolism. It facilitates conversion of acetyl-CoA and carnitine to acetylcarnitine and CoA respectively. This conversion facilitates peroxisomal β-oxidation by importing acetyl group for mitochondrial oxidation. | [Biochem/physiol Actions]
Carnitine acetyltransferase maintains the cellular and mitochondrial levels of acetyl-CoA, a key cofactor required for oxidative metabolism, by catalyzing an equilibrium between acetyl-CoA and acetyl-L-carnitine, a storage form of activated acetate. Carnitine acetyltransferase also maintains the pool of acetyl-CoA required for neuronal and nonneuronal acetylcholine production. |
|
Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
|