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ChemicalBook--->CAS DataBase List--->885703-64-0

885703-64-0

885703-64-0 Structure

885703-64-0 Structure
IdentificationBack Directory
[Name]

5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
[CAS]

885703-64-0
[Synonyms]

184748
C-FMS-IN-1
c-Fms inhibitor 1
cFmsIN1,c Fms IN 1
5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide
2-Furancarboxamide, 5-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(1-piperidinyl)phenyl]-
[Molecular Formula]

C22H27N5O2
[MDL Number]

MFCD30533480
[MOL File]

885703-64-0.mol
[Molecular Weight]

393.48
Chemical PropertiesBack Directory
[Boiling point ]

537.6±50.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 5 mg/mL (12.71 mM);Water : < 0.1 mg/mL (insoluble)
[form ]

Solid
[pka]

10.49±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1]. FMS kinase[1]

[References]

[1]. Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.

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