| Identification | Back Directory | [Name]
YIL 781 | [CAS]
875258-85-8 | [Synonyms]
CS-765
YIL 781
YIL 781, >=98%
YIL781, CID 23631116
YIL-781 hydrochloride
(S)-6-(4-Fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-methylquinazolin-4(3H)-one
6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone
4(3H)-Quinazolinone, 6-(4-fluorophenoxy)-2-Methyl-3-[[(3S)-1-(1-Methylethyl)-3-piperidinyl]Methyl]-
6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone hydrochloride | [Molecular Formula]
C24H28FN3O2 | [MDL Number]
MFCD27980545 | [MOL File]
875258-85-8.mol | [Molecular Weight]
409.5 |
| Chemical Properties | Back Directory | [Boiling point ]
532.3±58.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
H2O: soluble2mg/mL, clear (warmed) | [form ]
powder | [pka]
10.03±0.50(Predicted) | [color ]
white to yellow to light brown | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) |
| Hazard Information | Back Directory | [Uses]
YIL 781 is a ghrelin receptor antagonist useful in the treatment of obesity and diabetes. | [Biological Activity]
YIL-781 is a potent antagonist (Ki = 17 nM) of the growth hormone secretagogue receptor (GHS-R1). YIL-781 blocks ghrelin-induced reduction of insulin secretion in r at islets. In vivothe compound YIL-781 improves glucose tolerance and reduces weight gain. | [storage]
RT |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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