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ChemicalBook--->CAS DataBase List--->872506-67-7

872506-67-7

872506-67-7 Structure

872506-67-7 Structure
IdentificationBack Directory
[Name]

(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
[CAS]

872506-67-7
[Synonyms]

(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
[Molecular Formula]

C19H27ClN2O3S
[MDL Number]

MFCD11226407
[MOL File]

872506-67-7.mol
[Molecular Weight]

398.95
Hazard InformationBack Directory
[Description]

INCB13739 is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) for the treatment of type 2 diabetes. INCB-13739 has high selectivity for 11beta-HSD1 over other dehydrogenases and glucocorticoid and mineralocorticoid receptors, with prolonged pharmacodynamic activity and good pharmacokinetic/pharmacodynamic properties. INCB-13739 demonstrated improved hepatic and peripheral insulin sensitivity with a satisfactory reduction in fasting plasma glucose and cholesterol
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