| Identification | Back Directory | [Name]
IC87201 | [CAS]
866927-10-8 | [Synonyms]
IC87201
IC-87201
(IC87201
IC87201 >=98% (HPLC)
2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol
Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro- | [Molecular Formula]
C13H10Cl2N4O | [MDL Number]
MFCD28160570 | [MOL File]
866927-10-8.mol | [Molecular Weight]
309.15 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF:30.0(Max Conc. mg/mL);97.04(Max Conc. mM)
DMSO:29.0(Max Conc. mg/mL);93.81(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.81(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);3.23(Max Conc. mM) | [form ]
A solid | [color ]
Pink to red |
| Hazard Information | Back Directory | [Uses]
IC 87201 (cas# 866927-10-8) is a useful research chemical.IC 87201 is a small molecule inhibitor. It inhibited the in vitro binding of nNOS with PSD95, without inhibiting nNOS catalytic activity. | [Biological Activity]
IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction th at blocks NMDA-induced 3μ ,5μ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memoryspatial memoryand motor function in rats. |
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| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
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