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ChemicalBook--->CAS DataBase List--->86541-77-7

86541-77-7

86541-77-7 Structure

86541-77-7 Structure
IdentificationBack Directory
[Name]

(1R,3S)-Benazepril Hydrochloride
[CAS]

86541-77-7
[Synonyms]

Benazepril USP RC B
(1R,3S)-Benazepril HCl
Benner Pury hydrochloride
Benazepril Hydrochloridec
Benazepril Related CoMpound B
(1R,3S)-Benazepril Hydrochloride
Benazepril USP Related Compound B
Benazepril Impurity 8(Benazepril USP RC B)
(1R,3S)-Benazepril Hydrochloride USP/EP/BP
Benazepril Related Compound B as Hydrochloride
Benazepril USP Related Compound B as Hydrochloride
Benazepril Hydrochloride Impurity B as (1R,3S)-Enantiomer Hydrochloride
Benazepril Hydrochloride EP Impurity B as (1R,3S)-Enantiomer Hydrochloride
(3S)-3-[[(1R)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-y
2-((S)-3-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)aceticacidhydrochloride
1H-1-Benzazepine-1-acetic acid, 3-[[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-
1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,S*)]-
[Molecular Formula]

C24H28N2O5 HCl
[MDL Number]

MFCD01668249
[MOL File]

86541-77-7.mol
[Molecular Weight]

460.96
Chemical PropertiesBack Directory
[Melting point ]

181-183 °C(Solv: 2-butanone (78-93-3))
[storage temp. ]

2-8°C
[form ]

powder
Safety DataBack Directory
[HS Code ]

2933790002
Hazard InformationBack Directory
[Uses]

(1R,3S)-Benazepril Hydrochloride is an isomer of Benazepril (B119750), an angiotensin converting enzyme inhibitor and a antihypertensive agent.
[General Description]

Benazepril hydrochloride,(3S)-3-[[(1S)-1-carbethoxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid 3-ethylester hydrochloride (Lotensin), is metabolized rapidly to theactive diacid benazaprilat. As with the ACE prodrugs, nomutagenicity has been found, even though these drugs crossthe placenta.
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