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ChemicalBook--->CAS DataBase List--->863329-63-9

863329-63-9

863329-63-9 Structure

863329-63-9 Structure
IdentificationBack Directory
[Name]

Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI)
[CAS]

863329-63-9
[Synonyms]

C31H25N3O7
N4,3&rsquo
-methyleneCytidine
-Tribenzoyl,2&rsquo
Sofosbuvir Impurity 110
Sofosbuvir Methylene Impurity
N4,3’,5’-Tribenzoyl,2’-deoxy-2’-methylene Cytidine
Cytidine, N-benzoyl-2'-deoxy-2'-methylene-, 3',5'-dibenzoate
Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI)
(2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-methylenetetrahydrofuran-3-yl benzoate
[Molecular Formula]

C31H25N3O7
[MDL Number]

MFCD26961022
[MOL File]

863329-63-9.mol
[Molecular Weight]

551.55
Chemical PropertiesBack Directory
[Melting point ]

173.4-174.4 °C(Solv: ethanol (64-17-5))
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

7.61±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N4,3'',5''-Tribenzoyl,2''-deoxy-2''-methylene Cytidine is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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