Identification | Back Directory | [Name]
10-Hydroxycanthin-6-one | [CAS]
86293-41-6 | [Synonyms]
Ervine Aervine NSC 341583 10-Hydroxycanthin-6-one 6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,10-hydroxy- | [Molecular Formula]
C14H8N2O2 | [MDL Number]
MFCD28335422 | [MOL File]
86293-41-6.mol | [Molecular Weight]
236.23 |
Hazard Information | Back Directory | [Description]
The empirical formula for this alkaloid should read C21H24N203 and the structure
is that given above. This alkaloid has been fully described by Malikov and his
colleagues. It forms colourless crystals with m.p. 222-3°C from MeOH and has
the following specific rotations: [α]D- 57.3° (c 2.01, MeOH) and [α] D - 83.5°
(c 0.3, pyridine). Among the crystalline salts and derivatives that have been
prepared are the hydrochloride, m.p. 265-8°C; hydrobromide, m.p. 285-6°C;
hydriodide, m.p. 255-8°C and the methiodide, m.p. 258-260°C. | [Definition]
ChEBI: An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from Simaba multiflora, it exhibits antineoplastic activity. | [References]
Malikov, Yadishev, Yunusov, Khim. Prir. Soedin., 2, 338 (1966) |
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