| Identification | Back Directory | [Name]
QUININIC ACID | [CAS]
86-68-0 | [Synonyms]
Nsc 403610
QUININIC ACID
Cinchoninic Acid, 6-methoxy-
6-METHOXY-4-QUINOLINECARBOXYLIC ACID
6-METHOXYQUINOLINE-4-CARBOXYLIC ACID | [EINECS(EC#)]
237-014-3 | [Molecular Formula]
C11H9NO3 | [MDL Number]
MFCD00024013 | [MOL File]
86-68-0.mol | [Molecular Weight]
203.19 |
| Chemical Properties | Back Directory | [Melting point ]
280°C (decompose) | [Boiling point ]
341.49°C (rough estimate) | [density ]
1.2621 (rough estimate) | [refractive index ]
1.4950 (estimate) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Solubility Slightly soluble in water, cold ethanol, ether | [form ]
crystals | [pka]
5.53(at 25℃) | [color ]
Pale yellow | [PH Range]
Yellow I uorescent (4.0) to blue I uorescent (5.0) | [Merck ]
14,8062 | [Major Application]
Display device, antihypertensive food materials, nucleic acids, antimalarial agent, antimalerial agent | [CAS DataBase Reference]
86-68-0 |
| Questions And Answer | Back Directory | [Description]
6-Methoxy-4-quinolinecarboxylic Acid is a derivative of 4-quinolinecarboxylic acids, which is a potential antitumor (such as leukemia) and antiviral agent. It also has the potential to be used as immunosuppressive reagent as well as for the treatment of skin and epithelial diseases.
| [Sources]
https://www.sigmaaldrich.com/catalog/product/aldrich/174823?lang=en®ion=US
https://link.springer.com/article/10.1007/s11094-009-0187-1
https://patents.google.com/patent/US5084462A/en
https://patents.google.com/patent/US4861783A/en
|
| Hazard Information | Back Directory | [Uses]
6-methoxyquinoline-4-carboxylic Acid is used in the preparation of tetrahydroisoquinoline amides as multidrug resistance reversers. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 11, p. 803, 1946 DOI: 10.1021/jo01176a024 |
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