| Identification | Back Directory | [Name]
rel-(1R,4E,pR)-Cyclooct-4-enol | [CAS]
85081-69-2 | [Synonyms]
TCO-OH
(4E)-TCO-OH
trans-Cyclooctenol
(E)-Cyclooct-4-enol
TCO-OH,TCO-hydroxyl
(4E)-4-Cycloocten-1-ol
4-Cycloocten-1-ol, (4E)-
rel-(1R,4E,pR)-Cyclooct-4-enol | [Molecular Formula]
C8H14O | [MDL Number]
MFCD24386370 | [MOL File]
85081-69-2.mol | [Molecular Weight]
126.2 |
| Chemical Properties | Back Directory | [Boiling point ]
202.2±29.0 °C(Predicted) | [density ]
0.954±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO | [form ]
Liquid | [pka]
15.13±0.20(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
TCO-OH is a TCO intermediate allowed for further derivatizion | [Uses]
Hydroxyl modified cyclooctene derivative. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. | [reaction suitability]
reaction type: click chemistry
reagent type: linker |
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