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ChemicalBook--->CAS DataBase List--->82200-87-1

82200-87-1

82200-87-1 Structure

82200-87-1 Structure
IdentificationBack Directory
[Name]

5(S), 15(S)-DIHETE
[CAS]

82200-87-1
[Synonyms]

5,15-DiHETE
5(S), 15(S)-DIHETE
5(S),15(S)-DiHETE Lipid Maps MS Standard
5,15-dihydroxy-6,8,11,13-eicosatetraenoicacid
(5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-*eicosatetraen
(5S,15S)-DIHYDROXY-(6E,8Z,11Z,13E)-EICOS ATETRAENOI
5S,15S-DIHYDROXY-6E,8Z,11Z,13E-EICOSATETRAENOIC ACID
5(S),15(S)-DIHYDROXYEICOSA-6E,8Z,11Z,13E-TETRAENOIC ACID
5(S),15(S)-dihydroxy-6(E),8(Z),10(Z),13(E)-eicosatetraenoic aci
5(S),15(S)-Dihydroxy-6(E),8(Z),10(Z),13(E)-Eicosatetraenoic acid
6,8,11,13-Eicosatetraenoic acid, 5,15-dihydroxy-, (5S,6E,8Z,11Z,13E,15S)-
[Molecular Formula]

C20H32O4
[MDL Number]

MFCD00063589
[MOL File]

82200-87-1.mol
[Molecular Weight]

336.47
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
[form ]

Colorless liquid.
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
[Hazard Codes ]

F,Xi
[Risk Statements ]

11-36/37/38
[Safety Statements ]

16-26-36
Hazard InformationBack Directory
[Description]

5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.
[Uses]

5(S),15(S)-DiHETE is an enhancer of neutrophil degranulation and potent chemotaxin.
[Uses]

5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.
[Definition]

ChEBI: 5(S),15(S)-DiHETE is a DiHETE that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 15S-positions. It has a role as a rat metabolite and a human xenobiotic metabolite. It is a conjugate acid of a 5(S),15(S)-DiHETE(1-).
[storage]

Store at -20°C, protect from light
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