Identification | Back Directory | [Name]
O-(TETRADECYLPHOSPHORYL)CHOLINE 1.5 MM S | [CAS]
77733-28-9 | [Synonyms]
MAPCHO-14 Fos-choline-14 n-tetradecylphosphocholine CHOLINE TETRADECYL PHOSPHATE n-tetradecylphosphorylcholine N-TETRADECYLPHOSPHOCHOLINE;MAPCHO-14 n-Tetradecylphosphocholine (unlabelled) O-(Tetradecylphosphoryl)choline solution O-(TETRADECYLPHOSPHORYL)CHOLINE 1.5 MM S O-(Tetradecylphosphoryl)choline 1.5 mM Solution Tetradecyl (2-(trimethylammonio)ethyl) phosphate tetradecyl 2-(trimethylazaniumyl)ethyl phosphate Detergent Screening Solution 39/Fluka kit no 66317 2-[[hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl-, inner salt Ethanaminium,2-[[hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl-, inner salt | [EINECS(EC#)]
231-791-2 | [Molecular Formula]
C19H42NO4P | [MDL Number]
MFCD00171705 | [MOL File]
77733-28-9.mol | [Molecular Weight]
379.52 |
Chemical Properties | Back Directory | [Melting point ]
224-226 °C | [storage temp. ]
2-8°C | [solubility ]
DMF: 16 mg/ml; DMSO: 16 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 25 mg/ml | [form ]
A crystalline solid | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
Tetradecyl-phosphocholine is a detergent for membrane protein solubilization. | [Biological Activity]
n-Tetradecylphosphocholine (C14PC)a more stable analog of myristoyl lysophosphatidylcholineis an inhibitor of MARSA virulence. C14PC is a broad-spectrum inhibitor of Panton–Valentine leucocidin (PVL)LukED and α-toxin. C14PC protects primary human immune cells in vitro against cytolysis by PVL and α-toxin. C14PC can be used as a detergent for membrane solubilization. |
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