| Identification | Back Directory | [Name]
QUASSIN | [CAS]
76-78-8 | [Synonyms]
Balsam
QUASSIN
Nsc 36342
Alloquassin
4-epiquassin
Quassin (>
QUASSINPOWDER
Quassin (~90%)
Quassin (>95%)
Einecs 200-985-9
Reaxys ID: 1357246
PYROGALLIC ACID (RG)
11,16-trione,2,12-dimethoxy-picrasa-12-diene-1
2,12-Dimethoxypicrasa-2,12-diene-1,11,16-trione
Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy-
Quassin, mixture of isomers w/Neoquassin and Isoquassin
Quassin (Mixture of Quassin, Isoquassin and Neoquassin)
Quassin - isomeric mixture of isoquassin, neoquassin and quassin
(3aS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a
(3As,6ar,7as,8S,11as,11bs,11cs)-1,3A,4,5,6A,7,7A,8,11,11A,11B,11C-dodecahydro-2,10-dimethoxy-3,8,11A,11C-tetramethyldibenzo(de,G)chromene-1,5,11-trione | [EINECS(EC#)]
200-985-9 | [Molecular Formula]
C22H28O6 | [MDL Number]
MFCD00016884 | [MOL File]
76-78-8.mol | [Molecular Weight]
388.45 |
| Hazard Information | Back Directory | [Uses]
Quassin is a naturally occurring extract from quassia trees and is used in traditional chinese medicine for its antiulcerogenic properties. Quassin have also been used as an additive in soft drinks. | [Definition]
ChEBI: Quassin is a triterpenoid. | [in vivo]
Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats[1]. | Animal Model: | 35 females albino rats (150-170 g)[1] | | Dosage: | 0.1 mg/kg, 1.0 mg/kg and 2.0 mg/kg | | Administration: | Oral administration; daily; for 60 days | | Result: | There was a significant decrease in the weight of the ovary and uterus in all the groups relative to the control. There was also a significant decrease in serum estrogen levels in quassin treated rats. |
| [IC 50]
Plasmodium | [storage]
-20°C |
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