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ChemicalBook--->CAS DataBase List--->73080-51-0

73080-51-0

73080-51-0 Structure

73080-51-0 Structure
IdentificationBack Directory
[Name]

Repirinast
[CAS]

73080-51-0
[Synonyms]

Romet
MY-5116
REPIRINAST
3-Methylbutyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[5,6-c]quinoline-2-carboxylate
Isopentyl 7,8-diMethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-2-carboxylate
5,6-Dihydro-7,8-dimethyl-4,5-dioxo-4H-pyrano[3,2-c]quinoline-2-carboxylic acid 3-methylbutyl ester
4H-Pyrano[3,2-c]quinoline-2-carboxylic acid, 5,6-dihydro-7,8-diMethyl-4,5-dioxo-, 3-Methylbutyl Ester
[Molecular Formula]

C20H21NO5
[MDL Number]

MFCD00867034
[MOL File]

73080-51-0.mol
[Molecular Weight]

355.38
Chemical PropertiesBack Directory
[Melting point ]

236-241°
[Boiling point ]

488.42°C (rough estimate)
[density ]

1.2749 (rough estimate)
[refractive index ]

1.6000 (estimate)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Sparingly, Heated), Methanol (Slightly, Heated)
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

1.2mg/L(temperature not stated)
Hazard InformationBack Directory
[Usage]

Antiallergic.
[Description]

Repirinast is an orally-active antiallergic agent useful in the treatment of allergic asthma. Its activity is reportedly attributed to a metabolite, the corresponding free acid (MY-1250), which is 17 times more potent than disodium cromoglycate in inhibiting histamine release due to antigen-antibody reactions.
[Originator]

Mitsubishi (Japan)
[Uses]

Antiallergic.
[Definition]

ChEBI: Repirinast is an organic molecular entity.
[Brand name]

Romet
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1-Butanol
Safety DataBack Directory
[Toxicity]

LD50 in rats, mice (mg/kg): >5000 orally, >5000 s.c. both species (Nagase)
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